100 µg
Human anti-LukF-PV mAb (051)
Catalog Number: S200-002
Lot: See data sheet
Concentration: See data sheet
Description: Panton-Valentine leucocidin (PVL) is a cytotoxin released by Staphylococcus aureus and causes leukocyte lysis and tissue necrosis. PVL, is a bi-component exotoxin consisting of Leukocidin F (LukF) and Leukocidin S (LukS). Together, the two subunits join together to form beta barrel pores on the membrane of host immune cells such as white blood cells, monocytes and macrophages. The 34kDa structure of LukF has been solved in PDB 1PVL. Eliteimmune’s LukF targeting mAb 51 can be used in toxin neutralization assays (TNA) and is also a useful research tool for ELISAs and western blots.
Product Type: Human Monoclonal Antibody IgG1 subtype
Strain: Staphylococcus aureus
Synonyms: Gamma-toxin, gamma toxin, gamma hemolysin, hemolysin, PVL, LukF-PVL, leucocidin, leucocidin F, Panton-Valentine leucocidin, LukF, pore forming toxin, exotoxin
Expression Host: CHO
Tag: None
Purity: Antibody is purified using immobilized protein G.
Applications: ELISA, Western Blot, SDS-PAGE, toxin neutralization assays (TNA). Specific conditions should be optimized by end user.
Formulation: PBS
Storage: 4°C for immediate use, ≤-20°C for long-term storage. Avoid repeated freeze thaw cycles.
Shipped: Dry Ice
Intended Use: For research use only. Not intended for human, therapeutic, or diagnostic use. Buyer may not modify, sell, or transfer product for commercial use without written permission from Eliteimmune.
For customers located in the United States and EU, please purchase here.
Recommended Dilutions:
ELISA: Assay-dependent dilution. The antibody can be used for capture of LukF-PV in an indirect ELISA assay and Western blot detection.
WB: Suggested use dilution of 0.50 µg/mL
Neutralization: Assay-dependent dilution
Cross Reactivity: This antibody does not appear to cross react with S. aureus antigens Hla, LukS, SEA, or SEB, at the tested concentrations.
Gamma-toxin, gamma toxin, gamma hemolysin, hemolysin, PVL, LukF-PVL, leucocidin, leucocidin F, Panton-Valentine leucocidin, LukF, pore forming toxin, exotoxin